Cart
0
0.00 €
Compound Analysis
Key Nutrients
Active Folate (Vitamin B9)
L-5-methyltetrahydrofolate calcium [Extrafolate-S® Crystal]
400 µg
200% NRV *
200% NRV *
L-Leucine
Essential supportive amino acid
3 mg
Purity & Protocol
Recommended Dose
1 Capsule daily
Directions
Take before one of the main meals
With a glass of water (200 ml)
With a glass of water (200 ml)
Vegetable Capsule
Hypoallergenic natural polymer
HPMC
Flow Excipient
High-tolerance pure rice starch
Organic Starch
100% Vegan
Gluten Free
Lactose Free
High Cellular Bioavailability and Advanced Methylation
Nutricture® Methylfolate (Vitamin B9) utilizes the Extrafolate-S® Crystal biotechnological patent, a calcium salt of ultimate purity and structural stability. Unlike conventional synthetic folic acid, which requires a cascade of four complex enzymatic steps within the liver to become useful, L-5-methyltetrahydrofolate is the fully finished and biologically active form. This allows the organism to absorb it immediately, bypassing any genetic limitations (such as common mutations in the MTHFR gene), thereby ensuring optimal bioavailability even in individuals with significant absorption difficulties.
At a molecular level, this active folate acts as an indispensable cofactor in +cellular methylation cycles, crucial for converting homocysteine into methionine. Downregulating homocysteine in the bloodstream drastically reduces the risk of endothelial inflammation, actively protecting the integrity of the cardiovascular system. Furthermore, by effortlessly crossing the blood-brain barrier, it directly modulates the synthesis of critical neurotransmitters such as serotonin, dopamine, and norepinephrine, promoting excellent cognitive agility, enhancing focus, and stabilizing moods. It is a vital nutrient during pregnancy and preconception, as 5-MTHF directly intervenes in proper cell replication, the growth of maternal tissues, and significantly improves egg quality. Lastly, it optimizes the maturation of both white and red blood cells, strengthening natural defenses and combating cellular exhaustion.
Important contraindications and pharmacological warnings:
• Pernicious Anemia & Vitamin B12 Deficiency: Folate in therapeutic doses can correct hematological alterations (anemia) resulting from severe vitamin B12 deficiency, but it does not stop or repair the underlying neurological degeneration it causes. Therefore, its isolated use is contraindicated in individuals with suspected B12 deficiency without first determining and treating the root cause.
• Drug Interactions: If you are undergoing treatment with antiepileptic or anticonvulsant drugs (such as phenytoin, phenobarbital, or primidone), consult your physician, as folate can decrease the plasma concentrations of these medications and increase the risk of seizures. It also interferes with the action of certain cytotoxic antifolate agents like methotrexate.
• Pernicious Anemia & Vitamin B12 Deficiency: Folate in therapeutic doses can correct hematological alterations (anemia) resulting from severe vitamin B12 deficiency, but it does not stop or repair the underlying neurological degeneration it causes. Therefore, its isolated use is contraindicated in individuals with suspected B12 deficiency without first determining and treating the root cause.
• Drug Interactions: If you are undergoing treatment with antiepileptic or anticonvulsant drugs (such as phenytoin, phenobarbital, or primidone), consult your physician, as folate can decrease the plasma concentrations of these medications and increase the risk of seizures. It also interferes with the action of certain cytotoxic antifolate agents like methotrexate.
Informational Guidance Note
The information contained in this technical data sheet is provided exclusively for educational, reference, and informational guidance purposes. Under no circumstances does it substitute for the advice, diagnosis, or treatment of a health professional. Food supplements should not be used as substitutes for a balanced diet and a healthy lifestyle. Nutricture® promotes personal optimization under the supervision of qualified personnel.